The drug ALAMAIN has been developed by the Gentronic Drug Company
to lower blood pressure in people whose blood pressure is too high.
The drug has been thoroughly tested on animals with positive results.
The Gentronic Drug Company feels it is now time for the drug to
be tested on humans, and have contacted the Human Improvement Laboratory
to do the testing.
As chief research scientist at the Human Improvement Laboratory
(HIL) you have been assigned the task of developing the human testing
program for the new high blood pressure drug Alamain. You and your
assistants are to confer on the experimental design of this testing
program, and to write a report outlining the program. The report
is to be submitted to the chairperson of the HIL Drug-Testing Committee
for approval. Complete the following sections as you would include
them on your report.
- Using complete sentences state the hypothesis to be tested.
________________________________________________________________________________
________________________________________________________________________________
________________________________________________________________________________
________________________________________________________________________________
- A. How many people will be included in the experimental and
the control groups.
_______________________________________________________________________________
B. Using complete sentences explain your answer.
________________________________________________________________________________
________________________________________________________________________________
________________________________________________________________________________
________________________________________________________________________________
- Since there are several contributing factors that can affect
high blood pressure, list five factors that will
be constant between the experimental and the control groups.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Based on the factors list in Question 3, using complete sentences
explain why certain criteria need to be used in choosing the participants
in this study.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Once the list of participants has been created, using complete
sentences explain how they will be selected to be a member of
either the experimental or the control group.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Using complete sentences, explain the characteristics of what
must be given to the control group in place of the experimental
drug to act as a placebo , and why the participants should
be given this substance. Note: The drug Alamain is to be
developed as a pill to be taken orally with water.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Using complete sentences, suggest how often the drug is to be
administered to the experimental group, and the placebo control
group.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Using complete sentences, explain what measurements and/or tests
will be made on the experimental and control groups to judge the
efficiency of Alamain, and how often measurements and/or tests
will be taken.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
- Using complete sentences, explain what criteria will be used
to indicate the success or failure of the drug Alamain to reduce
high blood pressure in humans.
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________